New research from the University of Pennsylvania has identified a key regulator of skin cell turnover. The study is the first to demonstrate that LSD1 plays a role in the growth of non-melanoma skin cancers, and further that blocking LSD1 could be an effective method to target skin cancer. The study’s researchers explained: “Our study shows that targeting LSD1 can force the skin cells down a differentiation path, which could open the door to new topical therapies that can ultimately turn tumor cells into healthier, more normal cells."

The American Academy of Dermatology (AAD) and the National Psosriasis Foundation (NPF) recently published a joint guideline on the safety, efficacy, and appropriate clinical use of a broad range of phototherapy options. According to the guidelines, phototherapy is “an appropriate option for patients who have mild or moderate psoriasis or who have not attained an adequate or complete response with a systemic or biologic agent.”

Researchers from the Massachusetts Institute of Technology (MIT) have developed a microneedle skin patch capable of delivering medication to treat melanoma in one minute. In addition to holding significant potential for an effective melanoma vaccine, the technology could be applied to vaccinations for various other diseases as well. In a statement, the researchers shared on the technology’s current process: “Our patches elicit a robust antibody response in living mice and show promise in eliciting a strong immune response in human skin.”

 

 

Sept. 23, 2019 at 7pm EST

Treatment options for estrogen-deficient skin often carry adverse side effects and substantial health risks, however, recent research indicates the potential of a new compound to mitigate these harmful consequences while improving post-menopausal skin symptoms.